Μàñ Natural Biodegradable Polymers as Matrices in Transdermal Drug Delivery

Polymers are the backbone of a transdermal drug delivery system as they control the release of the drug from the device. Biodegradable polymers attracts the attention of its use as they can be degraded to non-toxic monomers and most important, a constant rate of drug release can be achieved from a biodegradable polymer based controlled release device. Natural polymers can be used as the means of achieving predetermined rates of drug delivery and their physico-chemical characteristics with the ease of availability provide a platform to use it as a polymer for transdermal drug delivery systems. These polymers may be used to formulate various controlled and targeted drug delivery system. *Corresponding author, mailing address: Kiran Sharma II E 96/A Nehru Nagar, Ghaziabad, UP 201001. Email: [email protected] R e v i e w P a p e r C o v e r e d i n O f f i c i a l P r o d u c t o f E l s e v i e r , T h e N e t h e r l a n d s Article History:-----------------------Date of Submission: 28-05-2011 Date of Acceptance: 06-06-2011 Conflict of Interest: NIL Source of Support: NONE Int. J. Drug Dev. & Res., April-June 2011, 3 (2): 85-103 Covered in Scopus & Embase, Elsevier 85 controlled drug release and hence it becomes extremely crucial to understand and select materials and techniques that would make it possible to control the drug release [4]. Controlled delivery of drug from the device to the biological system can be achieved by various means. Controlled drug release can also be achieved by embedding the drug onto a polymeric material and then releasing the drug in a predesigned controlled manner from the polymer into the blood stream. This is achieved by the use of transdermal drug delivery system that is made of polymeric